Blar i forfatter "Johansson, Kenth"

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    • Patient-tailored levothyroxine dosage with pharmacokinetic/pharmacodynamic modeling: A novel approach after total thyroidectomy 

      Brun, Vegard Heimly; Eriksen, Amund H.; Selseth, Ruth; Johansson, Kenth; Vik, Renate; Davidsen, Benedicte; Kaut, Michal; Hellemo, Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-07)
      Background: After seven decades of levothyroxine (LT4) replacement therapy, dosage adjustment still takes several months. We have developed a decision aid tool (DAT) that models LT4 pharmacometrics and enables patient-tailored dosage. The aim of this was to speed up dosage adjustments for patients after total thyroidectomy.<p> <p>Methods: The DAT computer program was developed with a group of 46 ...